Postmastectomy Radiation Therapy: Are We Ready to Individualize Radiation?
نویسندگان
چکیده
منابع مشابه
Radiobiological Optimization in Lung Stereotactic Body Radiation Therapy: Are We Ready to Apply Radiobiological Models?
Lung tumors are often associated with a poor prognosis although different schedules and treatment modalities have been extensively tested in the clinical practice. The complexity of this disease and the use of combined therapeutic approaches have been investigated and the use of high dose-rates is emerging as effective strategy. Technological improvements of clinical linear accelerators allow c...
متن کاملMounting Evidence for Postmastectomy Locoregional Radiation Therapy
Déjà vu All Over Again? Although a substantial number of women will suffer and die from breast cancer during the upcoming years, we clearly have made stepwise progress in treating patients with this cancer over the last 3 decades. Each of these steps of progress has led to what are glibly designated “paradigm shifts.” Perhaps the most hotly debated of these paradigms is the local vs systemic na...
متن کاملConsensus Statement on postmastectomy radiation therapy.
1. Reduction in the recurrence rate of clinically detectable local-regional disease by PMRT is evident. 2. The most recent randomized controlled trials, including two well-designed trials using modern radiation techniques, have shown a moderate and statistically significant improvement in survival. 3. Consultation with a radiation oncologist should occur in postmastectomy node-positive patients...
متن کاملMounting evidence for postmastectomy locoregional radiation therapy.
Postmastectomy locoregional radiation therapy markedly reduces the risk of locoregional recurrence. Several randomized trials, including two recently updated studies with 10- to 15-year follow-up, demonstrate an improvement in overall survival with radiation therapy. This improvement is seen in patients with one to three positive axillary lymph nodes, as well those with four positive nodes. The...
متن کاملThe use of blood biomarkers to predict radiation lung toxicity: a potential strategy to individualize thoracic radiation therapy.
BACKGROUND Radiation-induced lung toxicity (RILT) is an important dose-limiting toxicity during thoracic radiotherapy. Early prediction of radiation lung toxicity will allow physicians to determine a customized treatment regimen for each patient and deliver a radiation dose tailored to that individual's normal tissue sensitivity profile rather than to the average tolerance of the whole populati...
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ژورنال
عنوان ژورنال: International Journal of Breast Cancer
سال: 2018
ISSN: 2090-3170,2090-3189
DOI: 10.1155/2018/1402824